TY - JOUR
T1 - A black mould death
T2 - A case of fatal cerebral phaeohyphomycosis caused by Cladophialophora bantiana
AU - Howlett, Sarah
AU - Sullivan, Tadhg
AU - Abdolrasouli, Alireza
AU - Borman, Andrew M.
AU - Johnson, Elizabeth M.
AU - Lewis, Paul
AU - Baheerathan, Aravindhan
AU - Davies, Frances
AU - Sanderson, Frances
AU - Davies, Nicholas
AU - Singh-Curry, Victoria
N1 - Publisher Copyright:
© 2019
PY - 2019/6
Y1 - 2019/6
N2 - Cladophialophora bantiana is a neurotropic mould and primary cause of cerebral phaeohyphomycoses, which presents with brain abscesses in both immunocompromised and immunocompetent individuals. It is associated with high mortality due to delay in diagnosis and absence of standardised therapy. We present a case of fatal cerebral phaeohyphomycosis in a 67-year-old Caucasian man. Diagnosis was achieved by histopathological examination of brain tissue followed by conventional culture and molecular identification. We highlight diagnostic and treatment challenges involved.
AB - Cladophialophora bantiana is a neurotropic mould and primary cause of cerebral phaeohyphomycoses, which presents with brain abscesses in both immunocompromised and immunocompetent individuals. It is associated with high mortality due to delay in diagnosis and absence of standardised therapy. We present a case of fatal cerebral phaeohyphomycosis in a 67-year-old Caucasian man. Diagnosis was achieved by histopathological examination of brain tissue followed by conventional culture and molecular identification. We highlight diagnostic and treatment challenges involved.
KW - Cerebral phaeohyphomycoses
KW - Cladophialophora bantiana
KW - Dematiaceous fungi
KW - Gene sequencing
UR - http://www.scopus.com/inward/record.url?scp=85062227109&partnerID=8YFLogxK
U2 - 10.1016/j.mmcr.2019.02.004
DO - 10.1016/j.mmcr.2019.02.004
M3 - Article
AN - SCOPUS:85062227109
SN - 2211-7539
VL - 24
SP - 23
EP - 26
JO - Medical Mycology Case Reports
JF - Medical Mycology Case Reports
ER -
