Radiation, Chemical & Environmental Hazards

2025

Characterising Carbon Monoxide Household Exposure and Health Impacts in High- and Middle-Income Countries—A Rapid Literature Review, 2010–2024

Williams, S. V., Close, R., Piel, F. B., Barratt, B. & Crabbe, H., Jan 2025, In: International Journal of Environmental Research and Public Health. 22, 1, 110.

Research output: Contribution to journal › Review article › peer-review

Open Access

Ionizing Radiation May Induce Tumors Partly Through the Alteration or Regulation of Mismatch Repair Genes

Sun, M., Monahan, K., Moquet, J. & Barnard, S., Feb 2025, In: Cancers. 17, 4, 564.

Research output: Contribution to journal › Review article › peer-review

Open Access

Potential biomarkers of chronic low-dose radiation exposure for nuclear medicine technologists

Mbutu-Austin, I., Modarai, B., Ainsbury, E. & Terry, S. Y. A., 2025, In: International Journal of Radiation Biology. 101, 5, p. 453-466 14 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

2024

Addressing chemically-induced obesogenic metabolic disruption: selection of chemicals for in vitro human PPARα, PPARγ transactivation, and adipogenesis test methods

Ozcagli, E., Kubickova, B. & Jacobs, M. N., 2024, In: Frontiers in Endocrinology. 15, 1401120.

Research output: Contribution to journal › Review article › peer-review

Open Access

2 Citations (Scopus)

A new environmental public health practice to manage current and future global health challenges through education, training, and capacity building

Leonardi, G. S., Zeka, A., Ashworth, M., Bouland, C., Crabbe, H., Duarte-Davidson, R., Etzel, R. A., Giuashvili, N., Gökdemir, Ö., Hanke, W., van den Hazel, P., Jagals, P., Khan, E. A., Martin-Olmedo, P., Pett, J., Ruadze, E., Santamaria, M. G., Semenza, J. C., Sorensen, C. & Vardoulakis, S. & 2 others, Yip, F. & Lauriola, P., 2024, In: Frontiers in Public Health. 12, 1373490.

Research output: Contribution to journal › Review article › peer-review

2 Citations (Scopus)

Building competency to deal with environmental health challenges: experiences and a proposal

Leonardi, G. S., Zeka, A., Ashworth, M., Bouland, C., Crabbe, H., Duarte-Davidson, R., Etzel, R. A., Giuashvili, N., Gökdemir, Ö., Hanke, W., van den Hazel, P., Jagals, P., Khan, E. A., Martin-Olmedo, P., Pett, J., Ruadze, E., Santamaria, M. G., Semenza, J. C., Sorensen, C. & Vardoulakis, S. & 2 others, Yip, F. & Lauriola, P., 2024, In: Frontiers in Public Health. 12, 1373530.

Research output: Contribution to journal › Review article › peer-review

2 Citations (Scopus)

Consideration of hereditary effects in the radiological protection system: evolution and current status

Amrenova, A., Ainsbury, E., Baudin, C., Giussani, A., Lochard, J., Rühm, W., Scholz-Kreisel, P., Trott, K., Vaillant, L., Wakeford, R., Zölzer, F. & Laurier, D., 2024, In: International Journal of Radiation Biology. 100, 9, p. 1240-1252 13 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

4 Citations (Scopus)

Exposure to Tobacco-Specific Nitrosamines Among People Who Vape, Smoke, or do Neither: A Systematic Review and Meta-Analysis

Taylor, E., Simonavičius, E., McNeill, A., Brose, L. S., East, K., Marczylo, T. & Robson, D., 1 Mar 2024, In: Nicotine and Tobacco Research. 26, 3, p. 257-269 13 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

13 Citations (Scopus)

Health net-outcome objectives and approaches for spatial planning and development: a scoping review protocol

Stewart-Evans, J., Wilson, E., Langley, T., Hands, A. & Leonardi-Bee, J., 25 Jun 2024, In: JBI Evidence Synthesis. 22, 11, p. 2394-2403 10 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

The system of radiological protection and the UN sustainable development goals

Rühm, W., Applegate, K., Bochud, F., Laurier, D., Schneider, T., Bouffler, S., Cho, K., Clement, C., German, O., Hirth, G., Kai, M., Liu, S., Mayall, A., Romanov, S. & Wojcik, A., Nov 2024, In: Radiation and Environmental Biophysics. 63, 4, p. 469-482 14 p.

Research output: Contribution to journal › Review article › peer-review

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5 Citations (Scopus)

2023

Application of human biomonitoring data to support policy development, raise awareness and environmental public health protection among countries within the HBM4EU project

Contributors, Jun 2023, In: International Journal of Hygiene and Environmental Health. 251, 114170.

Research output: Contribution to journal › Review article › peer-review

9 Citations (Scopus)

A scoping review: What are the cellular mechanisms that drive the allergic inflammatory response to fungal allergens in the lung epithelium?

Goode, E. J. & Marczylo, E., Jun 2023, In: Clinical and Translational Allergy. 13, 6, e12252.

Research output: Contribution to journal › Review article › peer-review

Open Access

6 Citations (Scopus)

Development of a reference and proficiency chemical list for human steatosis endpoints in vitro

Kubickova, B. & Jacobs, M. N., 2023, In: Frontiers in Endocrinology. 14, 1126880.

Research output: Contribution to journal › Review article › peer-review

Open Access

5 Citations (Scopus)

Does air pollution confound associations between environmental noise and cardiovascular outcomes? - A systematic review

Eminson, K., Cai, Y. S., Chen, Y., Blackmore, C., Rodgers, G., Jones, N., Gulliver, J., Fenech, B. & Hansell, A. L., 1 Sept 2023, In: Environmental Research. 232, 116075.

Research output: Contribution to journal › Review article › peer-review

Open Access

25 Citations (Scopus)

Harmonized human biomonitoring in European children, teenagers and adults: EU-wide exposure data of 11 chemical substance groups from the HBM4EU Aligned Studies (2014–2021)

Govarts, E., Gilles, L., Rodriguez Martin, L., Santonen, T., Apel, P., Alvito, P., Anastasi, E., Andersen, H. R., Andersson, A. M., Andryskova, L., Antignac, J. P., Appenzeller, B., Barbone, F., Barnett-Itzhaki, Z., Barouki, R., Berman, T., Bil, W., Borges, T., Buekers, J. & Cañas-Portilla, A. & 91 others, Covaci, A., Csako, Z., Den Hond, E., Dvorakova, D., Fabelova, L., Fletcher, T., Frederiksen, H., Gabriel, C., Ganzleben, C., Göen, T., Halldorsson, T. I., Haug, L. S., Horvat, M., Huuskonen, P., Imboden, M., Jagodic Hudobivnik, M., Janasik, B., Janev Holcer, N., Karakitsios, S., Katsonouri, A., Klanova, J., Kokaraki, V., Kold Jensen, T., Koponen, J., Laeremans, M., Laguzzi, F., Lange, R., Lemke, N., Lignell, S., Lindroos, A. K., Lobo Vicente, J., Luijten, M., Makris, K. C., Mazej, D., Melymuk, L., Meslin, M., Mol, H., Montazeri, P., Murawski, A., Namorado, S., Niemann, L., Nübler, S., Nunes, B., Olafsdottir, K., Palkovicova Murinova, L., Papaioannou, N., Pedraza-Diaz, S., Piler, P., Plichta, V., Poteser, M., Probst-Hensch, N., Rambaud, L., Rauscher-Gabernig, E., Rausova, K., Remy, S., Riou, M., Rosolen, V., Rousselle, C., Rüther, M., Sarigiannis, D., Silva, M. J., Šlejkovec, Z., Snoj Tratnik, J., Stajnko, A., Szigeti, T., Tarazona, J. V., Thomsen, C., Tkalec, Ž., Tolonen, H., Trnovec, T., Uhl, M., Van Nieuwenhuyse, A., Vasco, E., Verheyen, V. J., Viegas, S., Vinggaard, A. M., Vogel, N., Vorkamp, K., Wasowicz, W., Weber, T., Wimmerova, S., Woutersen, M., Zimmermann, P., Zvonar, M., Koch, H., Kolossa-Gehring, M., Esteban López, M., Castaño, A., Stewart, L., Sepai, O. & Schoeters, G., Apr 2023, In: International Journal of Hygiene and Environmental Health. 249, 114119.

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79 Citations (Scopus)

208 Downloads (Pure)

HBM4EU results support the Chemicals’ Strategy for Sustainability and the Zero-Pollution Action Plan

Lobo Vicente, J., Ganzleben, C., Gasol, R., Marnane, I., Gilles, L., Buekers, J., Bessems, J., Colles, A., Gerofke, A., David, M., Barouki, R., Uhl, M., Sepai, O., Loots, I., Crabbé, A., Coertjens, D., Kolossa-Gehring, M. & Schoeters, G., Mar 2023, In: International Journal of Hygiene and Environmental Health. 248, 114111.

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14 Citations (Scopus)

103 Downloads (Pure)

Implementation and coordination of an ethics framework in HBM4EU – Experiences and reflections

Knudsen, L. E., Tolonen, H., Scheepers, P. T. J., Loots, I., Vorkamp, K., Hajeb, P., Sepai, O., Gilles, L., Splanemann, P., Weise, P. & Kolossa-Gehring, M., Mar 2023, In: International Journal of Hygiene and Environmental Health. 248, 114098.

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5 Citations (Scopus)

20 Downloads (Pure)

Increased Cell Proliferation as a Key Event in Chemical Carcinogenesis: Application in an Integrated Approach for the Testing and Assessment of Non-Genotoxic Carcinogenesis

Strupp, C., Corvaro, M., Cohen, S. M., Corton, J. C., Ogawa, K., Richert, L. & Jacobs, M. N., Sept 2023, In: International Journal of Molecular Sciences. 24, 17, 13246.

Research output: Contribution to journal › Review article › peer-review

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14 Citations (Scopus)

Indicators to support local public health to reduce the impacts of heat on health

Murage, P., Hajat, S., Macintyre, H. L., Leonardi, G. S., Ratwatte, P., Wehling, H., Petrou, G., Higlett, M., Hands, A. & Kovats, S., 16 Dec 2023, In: Environment International. 183, 108391.

Research output: Contribution to journal › Review article › peer-review

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7 Citations (Scopus)

Indoor air quality guidelines from across the world: An appraisal considering energy saving, health, productivity, and comfort

Dimitroulopoulou, S., Dudzińska, M. R., Gunnarsen, L., Hägerhed, L., Maula, H., Singh, R., Toyinbo, O. & Haverinen-Shaughnessy, U., Aug 2023, In: Environment International. 178, 108127.

Research output: Contribution to journal › Review article › peer-review

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69 Citations (Scopus)

New approach methodologies to facilitate and improve the hazard assessment of non-genotoxic carcinogens—a PARC project

Audebert, M., Assmann, A. S., Azqueta, A., Babica, P., Benfenati, E., Bortoli, S., Bouwman, P., Braeuning, A., Burgdorf, T., Coumoul, X., Debizet, K., Dusinska, M., Ertych, N., Fahrer, J., Fetz, V., Le Hégarat, L., López de Cerain, A., Heusinkveld, H. J., Hogeveen, K. & Jacobs, M. N. & 14 others, Luijten, M., Raitano, G., Recoules, C., Rundén-Pran, E., Saleh, M., Sovadinová, I., Stampar, M., Thibol, L., Tomkiewicz, C., Vettorazzi, A., Van de Water, B., El Yamani, N., Zegura, B. & Oelgeschläger, M., 2023, In: Frontiers in Toxicology. 5, 1220998.

Research output: Contribution to journal › Review article › peer-review

Open Access

10 Citations (Scopus)

PFAS levels and determinants of variability in exposure in European teenagers – Results from the HBM4EU aligned studies (2014–2021)

Richterová, D., Govarts, E., Fábelová, L., Rausová, K., Rodriguez Martin, L., Gilles, L., Remy, S., Colles, A., Rambaud, L., Riou, M., Gabriel, C., Sarigiannis, D., Pedraza-Diaz, S., Ramos, J. J., Kosjek, T., Snoj Tratnik, J., Lignell, S., Gyllenhammar, I., Thomsen, C. & Haug, L. S. & 13 others, Kolossa-Gehring, M., Vogel, N., Franken, C., Vanlarebeke, N., Bruckers, L., Stewart, L., Sepai, O., Schoeters, G., Uhl, M., Castaño, A., Esteban López, M., Göen, T. & Palkovičová Murínová, M., Jan 2023, In: International Journal of Hygiene and Environmental Health. 247, 114057.

Research output: Contribution to journal › Review article › peer-review

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64 Citations (Scopus)

The Cell Transformation Assay: A Historical Assessment of Current Knowledge of Applications in an Integrated Approach to Testing and Assessment for Non-Genotoxic Carcinogens

Colacci, A., Corvi, R., Ohmori, K., Paparella, M., Serra, S., Da Rocha Carrico, I., Vasseur, P. & Jacobs, M. N., Mar 2023, In: International Journal of Molecular Sciences. 24, 6, 5659.

Research output: Contribution to journal › Review article › peer-review

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15 Citations (Scopus)

The HBM4EU chromates study – Outcomes and impacts on EU policies and occupational health practices

Santonen, T., Louro, H., Bocca, B., Bousoumah, R., Duca, R. C., Fucic, A., Galea, K. S., Godderis, L., Göen, T., Iavicoli, I., Janasik, B., Jones, K., Leese, E., Leso, V., Ndaw, S., Poels, K., Porras, S. P., Ruggieri, F., Silva, M. J. & Van Nieuwenhuyse, A. & 6 others, Verdonck, J., Wasowicz, W., Tavares, A., Sepai, O., Scheepers, P. T. J. & Viegas, S., Mar 2023, In: International Journal of Hygiene and Environmental Health. 248, 114099.

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8 Citations (Scopus)

24 Downloads (Pure)

Using science to respond to public exposures from chemical hazards during emergencies in England

Urquhart, G. J., Symington, M., Foxall, K., Harrison, H. & Sepai, O., 1 Aug 2023, In: Toxicology Research. 12, 4, p. 539-543 5 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

1 Citation (Scopus)

Vancouver call for action to strengthen expertise in radiological protection worldwide

Rühm, W., Cho, K., Larsson, C. M., Wojcik, A., Clement, C., Applegate, K., Bochud, F., Bouffler, S., Cool, D., Hirth, G., Kai, M., Laurier, D., Liu, S., Romanov, S. & Schneider, T., May 2023, In: Radiation and Environmental Biophysics. 62, 2, p. 175-180 6 p.

Research output: Contribution to journal › Review article › peer-review

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19 Citations (Scopus)

2022

Analyses of Transcriptomics Cell Signalling for Pre-Screening Applications in the Integrated Approach for Testing and Assessment of Non-Genotoxic Carcinogens

Oku, Y., Madia, F., Lau, P., Paparella, M., McGovern, T., Luijten, M. & Jacobs, M. N., Nov 2022, In: International Journal of Molecular Sciences. 23, 21, 12718.

Research output: Contribution to journal › Review article › peer-review

Open Access

11 Citations (Scopus)

Cancer risks among studies of medical diagnostic radiation exposure in early life without quantitative estimates of dose

Little, M. P., Wakeford, R., Bouffler, S. D., Abalo, K., Hauptmann, M., Hamada, N. & Kendall, G. M., 1 Aug 2022, In: Science of the Total Environment, The. 832, 154723.

Research output: Contribution to journal › Review article › peer-review

19 Citations (Scopus)

Candidate Proficiency Test Chemicals to Address Industrial Chemical Applicability Domains for in vitro Human Cytochrome P450 Enzyme Induction

Jacobs, M. N., Kubickova, B. & Boshoff, E., 2022, In: Frontiers in Toxicology. 4, 880818.

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Open Access

5 Citations (Scopus)

Chemicals in European residences – Part I: A review of emissions, concentrations and health effects of volatile organic compounds (VOCs)

Halios, C. H., Landeg-Cox, C., Lowther, S. D., Middleton, A., Marczylo, T. & Dimitroulopoulou, S., 15 Sept 2022, In: Science of the Total Environment, The. 839, 156201.

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Open Access

124 Citations (Scopus)

Determination of metallic nanoparticles in biological samples by single particle ICP-MS: A systematic review from sample collection to analysis

Laycock, A., Clark, N. J., Clough, R., Smith, R. & Handy, R. D., 13 Jan 2022, In: Environmental Science: Nano. 9, 2, p. 420-453 34 p.

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36 Citations (Scopus)

66 Downloads (Pure)

Reactive Oxygen Species in the Adverse Outcome Pathway Framework: Toward Creation of Harmonized Consensus Key Events

on behalf of The Mystery of ROS Consortium, 2022, In: Frontiers in Toxicology. 4, 887135.

Research output: Contribution to journal › Review article › peer-review

Open Access

23 Citations (Scopus)

Small airway susceptibility to chemical and particle injury

Fransen, L. F. H. & Leonard, M. O., 2022, In: Respiration. 101, 3, p. 321-333 13 p.

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Open Access

6 Citations (Scopus)

Workplace interventions to reduce the risk of SARS-CoV-2 infection outside of healthcare settings

Pizarro, A. B., Persad, E., Durao, S., Nussbaumer-Streit, B., Engela-Volker, J. S., McElvenny, D., Rhodes, S., Stocking, K., Fletcher, T., Martin, C., Noertjojo, K., Sampson, O., Verbeek, J. H., Jørgensen, K. J. & Bruschettini, M., 6 May 2022, In: The Cochrane database of systematic reviews. 2022, 5, CD015112.

Research output: Contribution to journal › Review article › peer-review

Open Access

2 Citations (Scopus)

2021

A 10-year follow-up study of yearly indoor radon measurements in homes, review of other studies and implications on lung cancer risk estimates

Antignani, S., Venoso, G., Ampollini, M., Caprio, M., Carpentieri, C., Di Carlo, C., Caccia, B., Hunter, N. & Bochicchio, F., 25 Mar 2021, In: Science of the Total Environment, The. 762, 12 p., 144150.

Research output: Contribution to journal › Review article › peer-review

Open Access

31 Citations (Scopus)

A critical review of the epidemiological evidence of effects of air pollution on dementia, cognitive function and cognitive decline in adult population

Delgado-Saborit, J. M., Guercio, V., Gowers, A. M., Shaddick, G., Fox, N. C. & Love, S., 25 Feb 2021, In: Science of the Total Environment, The. 757, 27 p., 143734.

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Open Access

159 Citations (Scopus)

Adverse outcome pathways, key events, and radiation risk assessment

Preston, R. J., Rühm, W., Azzam, E. I., Boice, J. D., Bouffler, S., Held, K. D., Little, M. P., Shore, R. E., Shuryak, I. & Weil, M. M., 3 Jun 2021, In: International Journal of Radiation Biology. 97, 6, p. 804-814 11 p.

Research output: Contribution to journal › Review article › peer-review

18 Citations (Scopus)

Air quality around schools: Part I - A comprehensive literature review across high-income countries

Osborne, S., Uche, O., Mitsakou, C., Exley, K. & Dimitroulopoulou, S., May 2021, In: Environmental Research. 196, 19 p., 110817.

Research output: Contribution to journal › Review article › peer-review

41 Citations (Scopus)

Assessing the exposure to air pollution during transport in urban areas – Evidence review

Mitsakou, C., Adamson, J. P., Doutsi, A., Brunt, H., Jones, S. J., Gowers, A. M. & Exley, K., 9 Apr 2021, (E-pub ahead of print) In: Journal of Transport and Health. 21, 101064.

Research output: Contribution to journal › Review article › peer-review

26 Citations (Scopus)

EFFECTIVE DOSE COEFFICIENTS for RADON and PROGENY: A REVIEW of ICRP and UNSCEAR VALUES

Marsh, J. W., Tomášek, L., Laurier, D. & Harrison, J. D., 1 Jun 2021, In: Radiation Protection Dosimetry. 195, 1, p. 1-20 20 p.

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11 Citations (Scopus)

Exposure to indoor and outdoor air pollution from solid fuel combustion and respiratory outcomes in children in developed countries: a systematic review and meta-analysis

Guercio, V., Pojum, I. C., Leonardi, G., Shrubsole, C., Gowers, A. M., Dimitroulopoulou, S. & Exley, K. S., 10 Feb 2021, In: Science of the Total Environment, The. 755, 15 p., 142187.

Research output: Contribution to journal › Review article › peer-review

36 Citations (Scopus)

Gene Expression Changes in Irradiated Baboons: A Summary and Interpretation of a Decade of Findings

Port, M., Hérodin, F., Drouet, M., Valente, M., Majewski, M., Ostheim, P., Lamkowski, A., Schüle, S., Forcheron, F., Tichy, A., Sirak, I., Malkova, A., Becker, B. V., Veit, D. A., Waldeck, S., Badie, C., O'Brien, G., Christiansen, H., Wichmann, J. & Beutel, G. & 3 others, Davidkova, M., Doucha-Senf, S. & Abend, M., 1 Jun 2021, In: Radiation Research. 195, 6, p. 501-521 21 p.

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20 Citations (Scopus)

Gene expression for biodosimetry and effect prediction purposes: promises, pitfalls and future directions–key session ConRad 2021

Ostheim, P., Amundson, S. A., Badie, C., Bazyka, D., Evans, A. C., Ghandhi, S. A., Gomolka, M., López Riego, M., Rogan, P. K., Terbrueggen, R., Woloschak, G. E., Zenhausern, F., Kaatsch, H. L., Schüle, S., Ullmann, R., Port, M. & Abend, M., 18 Oct 2021, (E-pub ahead of print) In: International Journal of Radiation Biology. 98, 5, p. 843-854 12 p.

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15 Citations (Scopus)

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Highlighting the gaps in hazard and risk assessment of unregulated Endocrine Active Substances in surface waters: retinoids as a European case study

Kubickova, B., Ramwell, C., Hilscherova, K. & Jacobs, M. N., 1 Feb 2021, In: Environmental Sciences Europe. 33, 1, 38 p., 20.

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13 Citations (Scopus)

Identification of novel simulants for toxic industrial chemicals and chemical warfare agents for human decontamination studies: A systematic review and categorisation of physicochemical characteristics

James, T., Collins, S. & Marczylo, T., 17 Aug 2021, In: International Journal of Environmental Research and Public Health. 18, 16, 8681.

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4 Citations (Scopus)

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Integration of epigenetic mechanisms into non-genotoxic carcinogenicity hazard assessment: Focus on DNA methylation and histone modifications

Daniel, D., Vasseur, P., Jacobs, A., Aguila, M. C., Ertych, N. & Jacobs, M. N., 11 Oct 2021, In: International Journal of Molecular Sciences. 22, 20, 10969.

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31 Citations (Scopus)

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Mass casualty decontamination for chemical incidents: Research outcomes and future priorities

Collins, S., James, T., Carter, H., Symons, C., Southworth, F., Foxall, K., Marczylo, T. & Amlot, R., 2 Mar 2021, In: International Journal of Environmental Research and Public Health. 18, 6, p. 1-19 19 p., 3079.

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15 Citations (Scopus)

Portable air purification: Review of impacts on indoor air quality and health

Cheek, E., Guercio, V., Shrubsole, C. & Dimitroulopoulou, S., 20 Apr 2021, In: Science of the Total Environment, The. 766, 41 p., 142585.

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141 Citations (Scopus)

Radiation-Induced Immunity and Toxicities: The Versatility of the cGAS-STING Pathway

Constanzo, J., Faget, J., Ursino, C., Badie, C. & Pouget, J. P., 17 May 2021, In: Frontiers in Immunology. 12, 17 p., 680503.

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51 Citations (Scopus)

195 Downloads (Pure)

Systematic review of human poisoning and toxic exposures in Myanmar

Cook, M. A., Jagpal, P. S., Pwint, K. H., San, L. L., Thein, S. S. K., Pyone, T., Thit, W. M. M., Bradberry, S. M. & Collins, S., 1 Apr 2021, In: International Journal of Environmental Research and Public Health. 18, 7, 16 p., 3576.

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