HPO DG Private Office

2024

Descriptive Epidemiology of Travel and Non-Travel Related SARS-CoV-2 Gamma (P.1/501Y.V3) Variant Cases in England, 2021

Abdul Aziz, N., Twohig, K., Sinnathamby, M., Zaidi, A., Aliabadi, S., Groves, N., Nash, S., Thelwall, S. & Dabrera, G., May 2024, In: Influenza and other Respiratory Viruses. 18, 5, e13308.

Research output: Contribution to journal › Article › peer-review

Open Access

Postpandemic Sentinel Surveillance of Respiratory Diseases in the Context of the World Health Organization Mosaic Framework: Protocol for a Development and Evaluation Study Involving the English Primary Care Network 2023-2024

Gu, X., Watson, C., Agrawal, U., Whitaker, H., Elson, W. H., Anand, S., Borrow, R., Buckingham, A., Button, E., Curtis, L., Dunn, D., Elliot, A. J., Ferreira, F., Goudie, R., Hoang, U., Hoschler, K., Jamie, G., Kar, D., Kele, B. & Leston, M. & 21 others, Linley, E., Macartney, J., Marsden, G. L., Okusi, C., Parvizi, O., Quinot, C., Sebastianpillai, P., Sexton, V., Smith, G., Suli, T., Thomas, N. P. B., Thompson, C., Todkill, D., Wimalaratna, R., Inada-Kim, M., Andrews, N., Tzortziou-Brown, V., Byford, R., Zambon, M., Lopez-Bernal, J. & Lusignan, S. D., 3 Apr 2024, In: JMIR Public Health and Surveillance. 10, e52047.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Citations (Scopus)

2023

Descriptive epidemiology of SARS-CoV-2 Beta (B.1.351) variant cases in England, December 2020 to June 2022

Sinnathamby, M. A., Zaidi, A., Twohig, K. A., Aliabadi, S., Aziz, N. A., Groves, N., Gallagher, E., Thelwall, S. & Dabrera, G., Nov 2023, In: Influenza and other Respiratory Viruses. 17, 11, e13204.

Research output: Contribution to journal › Article › peer-review

Open Access

Effects of Second Dose of SARS-CoV-2 Vaccination on Household Transmission, England

Zaidi, A., Harris, R., Hall, J., Woodhall, S., Andrews, N., Dunbar, K., Lopez-Bernal, J. & Dabrera, G., Jan 2023, In: Emerging Infectious Diseases. 29, 1, p. 127-132 6 p.

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Open Access

6 Citations (Scopus)

Investigation of hospital discharge cases and SARS-CoV-2 introduction into Lothian care homes

The COVID-19 Genomics UK (COG-UK) consortium, May 2023, In: Journal of Hospital Infection. 135, p. 28-36 9 p.

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Open Access

2 Citations (Scopus)

Rapid rise in COVID-19 among young people in England – learning for the future

Twohig, K. A., Zaidi, A., Campos-Matos, I., Hope, R., Hall, J., Chudasama, D., Sinnathamby, M., Fitzpatrick, J., Dabrera, G. & Mohammed, H., May 2023, In: Public Health. 218, p. 136-138 3 p.

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Open Access

1 Citation (Scopus)

Representativeness of whole-genome sequencing approaches in England: the importance for understanding inequalities associated with SARS-CoV-2 infection

Twohig, K. A., Harman, K., Zaidi, A., Aliabadi, S., Nash, S. G., Sinnathamby, M., Harrison, I., Gallagher, E., Groves, N., Schwach, F., Pearson, C., Thornton, A., Myers, R., Chand, M., Thelwall, S. & Dabrera, G., 20 Sept 2023, In: Epidemiology and Infection. 151, e169.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Citations (Scopus)

The SARS-CoV-2 Alpha variant was associated with increased clinical severity of COVID-19 in Scotland: A genomics-based retrospective cohort analysis

The COVID-19 Genomics UK (COG-UK) consortium, Apr 2023, In: PLoS ONE. 18, 4, e0284187.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Citations (Scopus)

2022

A Persistent Tuberculosis Outbreak in the UK Is Characterized by Hydrophobic fadB4-Deficient Mycobacterium tuberculosis That Replicates Rapidly in Macrophages

Farzand, R., Haigh, R. D., Monk, P., Haldar, P., Patel, H., Pareek, M., Verma, R., Barer, M. R., Woltmann, G., Ahyow, L., Jagatia, H., Decker, J., Mukamolova, G. V., Cooper, A. M., Garton, N. J. & O’Hare, H. M., Dec 2022, In: mBio. 13, 6

Research output: Contribution to journal › Article › peer-review

Open Access

1 Citation (Scopus)

Assessment of mortality and hospital admissions associated with confirmed infection with SARS-CoV-2 Alpha variant: a matched cohort and time-to-event analysis, England, October to December 2020

Dabrera, G., Allen, H., Zaidi, A., Flannagan, J., Twohig, K., Thelwall, S., Marchant, E., Aziz, N. A., Lamagni, T., Myers, R., Charlett, A., Capelastegui, F., Chudasama, D., Clare, T., Coukan, F., Sinnathamby, M., Ferguson, N., Hopkins, S., Chand, M. & Hope, R. & 1 others, Kall, M., 19 May 2022, In: Eurosurveillance. 27, 20

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Open Access

8 Citations (Scopus)

COVID-19 due to the B.1.617.2 (Delta) variant compared to B.1.1.7 (Alpha) variant of SARS-CoV-2: a prospective observational cohort study

The COVID-19 Genomics U. K. (COG-UK) Consortium, Dec 2022, In: Scientific Reports. 12, 1, 10904.

Research output: Contribution to journal › Article › peer-review

Open Access

43 Citations (Scopus)

Evaluation of prognostic risk models for postoperative pulmonary complications in adult patients undergoing major abdominal surgery: a systematic review and international external validation cohort study

STARSurg Collaborative and TASMAN Collaborative, Jul 2022, In: The Lancet Digital Health. 4, 7, p. e520-e531

Research output: Contribution to journal › Article › peer-review

Open Access

24 Citations (Scopus)

Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort study

COVID-19 Genomics UK (COG-UK) Consortium, 1 Jan 2022, In: The Lancet Infectious Diseases. 22, 1, p. 35-42 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

561 Citations (Scopus)

Household transmission of COVID-19 cases associated with SARS-CoV-2 delta variant (B.1.617.2): national case-control study

the COVID-19 Genomics UK (COG-UK Consortium), Jan 2022, In: The Lancet Regional Health - Europe. 12, 100252.

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121 Citations (Scopus)

68 Downloads (Pure)

Increased Residential Clustering of COVID-19 Cases Associated With SARS-CoV-2 Variant of Concern B.1.1.7

Flannagan, J., Twohig, K. A., Carter, E., Chudasama, D. Y., Lamagni, T. & Dabrera, G., 1 Jul 2022, In: Epidemiology. 33, 4, p. 465-469 5 p.

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

PrEP use and unmet PrEP-need among men who have sex with men in London prior to the implementation of a national PrEP programme, a cross-sectional study from June to August 2019

Ogaz, D., Logan, L., Curtis, T. J., McDonagh, L., Guerra, L., Bradshaw, D., Patel, P., Macri, C., Murphy, G., Noel Gill, O., Johnson, A. M., Nardone, A. & Burns, F., 3 Jun 2022, In: BMC Public Health. 22, 1, 1105.

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10 Citations (Scopus)

17 Downloads (Pure)

Recurrent SARS-CoV-2 mutations in immunodeficient patients

The COVID-19 Genomics UK (COG-UK) consortium, 2022, In: Virus Evolution. 8, 2, veac050.

Research output: Contribution to journal › Article › peer-review

Open Access

55 Citations (Scopus)

SARS Antibody Testing in Children: Development of Oral Fluid Assays for IgG Measurements

Hoschler, K., Ijaz, S., Andrews, N., Ho, S., Dicks, S., Jegatheesan, K., Poh, J., Warrener, L., Kankeyan, T., Baawuah, F., Beckmann, J., Okike, I. O., Ahmad, S., Garstang, J., Brent, A. J., Brent, B., Aiano, F., Brown, K. E., Ramsay, M. E. & Brown, D. & 3 others, Parry, J. V., Ladhani, S. N. & Zambon, M., Feb 2022, In: Microbiology Spectrum. 10, 1, 12 p., ARTN e00786-21.

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17 Citations (Scopus)

44 Downloads (Pure)

SARS-CoV-2 lineage dynamics in England from September to November 2021: high diversity of Delta sub-lineages and increased transmissibility of AY.4.2

The COVID-19 Genomics UK (COG-UK) consortium, Dec 2022, In: BMC Infectious Diseases. 22, 1, 647.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Citations (Scopus)

SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway

PITCH Consortium & The COVID-19 Genomics UK (COG-UK) consortium, 1 Aug 2022, In: Nature Microbiology. 7, 8, p. 1161-1179 19 p.

Research output: Contribution to journal › Article › peer-review

Open Access

415 Citations (Scopus)

SARS-CoV-2 Testing in the Community: Testing Positive Samples with the TaqMan SARS-CoV-2 Mutation Panel To Find Variants in Real Time

The COVID-19 Genomics UK (COG-UK) consortium, Apr 2022, In: Journal of Clinical Microbiology. 60, 4

Research output: Contribution to journal › Article › peer-review

Open Access

9 Citations (Scopus)

Spatial growth rate of emerging SARS-CoV-2 lineages in England, September 2020-December 2021

The COVID-19 Genomics UK (COG-UK) consortium, 20 Jul 2022, In: Epidemiology and Infection. 150, e145.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Citations (Scopus)

Transmission dynamics of COVID-19 in household and community settings in the United Kingdom, January to March 2020

Lopez Bernal, J., Panagiotopoulos, N., Byers, C., Garcia Vilaplana, T., Boddington, N., Zhang, X. S., Charlett, A., Elgohari, S., Coughlan, L., Whillock, R., Logan, S., Bolt, H., Sinnathamby, M., Letley, L., MacDonald, P., Vivancos, R., Edeghere, O., Anderson, C., Paranthaman, K. & Cottrell, S. & 5 others, McMenamin, J., Zambon, M., Dabrera, G., Ramsay, M. & Saliba, V., 14 Apr 2022, In: Eurosurveillance. 27, 15

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18 Citations (Scopus)

107 Downloads (Pure)

2021

Acceptability and usability of HIV self-tests in two European countries: findings from surveys of clients at non-governmental organisations in Lithuania and Italy

Nash, S. G., Maffeo, M., Likatavicius, G., Cosmaro, L., Rudaitis, K., Lapsinov, A., Enayat, Q., Delpech, V. & Kall, M., 13 Sept 2021, In: BMC Infectious Diseases. 21, 844.

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5 Citations (Scopus)

15 Downloads (Pure)

A cluster of Shiga Toxin-producing Escherichia coli O157:H7 highlights raw pet food as an emerging potential source of infection in humans

Kaindama, L., Jenkins, C., Aird, H., Jorgensen, F., Stoker, K. & Byrne, L., 6 May 2021, (E-pub ahead of print) In: Epidemiology and Infection. 149, e124.

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17 Citations (Scopus)

45 Downloads (Pure)

Antibody responses to SARS-CoV-2 vaccines in 45,965 adults from the general population of the United Kingdom

the COVID-19 Infection Survey team, Wei, J., Stoesser, N., Matthews, P. C., Ayoubkhani, D., Studley, R., Bell, I., Bell, J. I., Newton, J. N., Farrar, J., Diamond, I., Rourke, E., Howarth, A., Marsden, B. D., Hoosdally, S., Jones, E. Y., Stuart, D. I., Crook, D. W., Peto, T. E. A. & Pouwels, K. & 4 others, Eyre, D. W., Walker, A. S., Robotham, J. & Birrell, P., Sept 2021, In: Nature Microbiology. 6, 9, p. 1140-1149 10 p.

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225 Citations (Scopus)

13 Downloads (Pure)

A randomized controlled trial to test the effect of simplified guidance with visuals on comprehension of COVID-19 guidelines and intention to stay home if symptomatic

Gold, N., Watson, R., Weston, D., Greaves, F. & Amlot, R., 10 May 2021, In: BMC Public Health. 21, 1, 13 p., 892.

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3 Citations (Scopus)

20 Downloads (Pure)

Augmenting contact matrices with time-use data for fine-grained intervention modelling of disease dynamics: A modelling analysis

PHE Joint modelling group, van Leeuwen, E., Sandmann, F., Charlett, A., Presanis, A., Ferguson, B., DeAngelis, D., Bays, D., Vynnycky, E., Agnew, E., Bennett, E., Gillingham, E., Lewis, J., Carruthers, J., Shingleton, J., Gent, N., Birrell, P., White, P., Shadwell, S. & Dyke, S. & 1 others, Finnie, T., 1 Sept 2021, (E-pub ahead of print) In: Statistical Methods in Medical Research. 31, 9, p. 1704-1715 12 p., 09622802211037078.

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2 Citations (Scopus)

Comparing aerosol concentrations and particle size distributions generated by singing, speaking and breathing

Gregson, F. K. A., Watson, N. A., Orton, C. M., Haddrell, A. E., McCarthy, L. P., Finnie, T. J. R., Gent, R., Donaldson, G. C., Shah, P. L., Calder, J. D., Bzdek, B. R., Costello, D. & Reid, J. P., 21 Apr 2021, In: Aerosol Science and Technology. 55, 6, p. 681-691 11 p.

Research output: Contribution to journal › Article › peer-review

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141 Citations (Scopus)

COVID-19 mortality among people with diagnosed HIV compared to those without during the first wave of the COVID-19 pandemic in England

Brown, A. E., Croxford, S. E., Nash, S., Khawam, J., Kirwan, P., Kall, M., Bradshaw, D., Sabin, C., Miller, R. F., Post, F. A., Harding, R., Collins, S., Waters, L., Asboe, D., Chadwick, D. R., Delpech, V. & Sullivan, A. K., 15 Sept 2021, (E-pub ahead of print) In: HIV Medicine. 23, 1, p. 90-102 13 p.

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14 Citations (Scopus)

COVID-19 vaccine coverage in health-care workers in England and effectiveness of BNT162b2 mRNA vaccine against infection (SIREN): a prospective, multicentre, cohort study

SIREN Study Group, Hall, V. J., Foulkes, S., Saei, A., Andrews, N., Oguti, B., Charlett, A., Wellington, E., Stowe, J., Gillson, N., Atti, A., Islam, J., Karagiannis, I., Munro, K., Khawam, J., Chand-Kumar, M., Brown, C. S., Ramsay, M., Lopez-Bernal, J. & Hopkins, S., 8 May 2021, In: The Lancet. 397, 10286, p. 1725-1735 11 p.

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538 Citations (Scopus)

CT threshold values, a proxy for viral load in community sars-cov-2 cases, demonstrate wide variation across populations and over time

Walker, A. S., Pritchard, E., House, T., Robotham, J., Birrell, P., Bell, I., Bell, J. I., Newton, J. N., Farrar, J., Diamond, I., Studley, R., Hay, J., Vihta, K. D., Peto, T. E. A., Stoesser, N., Matthews, P. C., Eyre, D. W. & Pouwels, K., 12 Jul 2021, In: eLife. 10, e64683.

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71 Citations (Scopus)

13 Downloads (Pure)

Daily testing for contacts of individuals with SARS-CoV-2 infection and attendance and SARS-CoV-2 transmission in English secondary schools and colleges: an open-label, cluster-randomised trial

Young, B. C., Eyre, D. W., Kendrick, S., White, C., Smith, S., Beveridge, G., Nonnenmacher, T., Ichofu, F., Hillier, J., Oakley, S., Diamond, I., Rourke, E., Dawe, F., Day, I., Davies, L., Staite, P., Lacey, A., McCrae, J., Jones, F. & Kelly, J. & 11 others, Bankiewicz, U., Tunkel, S., Ovens, R., Chapman, D., Bhalla, V., Marks, P., Hicks, N., Fowler, T., Hopkins, S., Yardley, L. & Peto, T. E. A., 2 Oct 2021, In: The Lancet. 398, 10307, p. 1217-1229 13 p.

Research output: Contribution to journal › Article › peer-review

79 Citations (Scopus)

Dose-dependent response to infection with SARS-CoV-2 in the ferret model and evidence of protective immunity

Ryan, K. A., Bewley, K. R., Fotheringham, S. A., Slack, G. S., Brown, P., Hall, Y., Wand, N. I., Marriott, A. C., Cavell, B. E., Tree, J. A., Allen, L., Aram, M. J., Bean, T. J., Brunt, E., Buttigieg, K. R., Carter, D. P., Cobb, R., Coombes, N. S., Findlay-Wilson, S. J. & Godwin, K. J. & 35 others, Gooch, K. E., Gouriet, J., Halkerston, R., Harris, D. J., Hender, T. H., Humphries, H. E., Hunter, L., Ho, C. M. K., Kennard, C. L., Leung, S., Longet, S., Ngabo, D., Osman, K. L., Paterson, J., Penn, E. J., Pullan, S., Rayner, E., Skinner, O., Steeds, K., Taylor, I., Tipton, T., Thomas, S., Turner, C., Watson, R. J., Wiblin, N. R., Charlton, S., Hallis, B., Hiscox, J. A., Funnell, S., Dennis, M. J., Whittaker, C. J., Catton, M. G., Druce, J., Salguero Bodes, F. J. & Carroll, M., 4 Jan 2021, In: Nature Communications. 12, 1, 13 p., 81.

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134 Citations (Scopus)

80 Downloads (Pure)

Dose–Response Modeling: Extrapolating From Experimental Data to Real-World Populations

Pratt, A., Bennett, E., Gillard, J., Leach, S. & Hall, I., Jan 2021, In: Risk Analysis. 41, 1, p. 67-78 12 p.

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1 Citation (Scopus)

Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant

Bernal, J. L., Andrews, N., Gower, C., Gallagher, E., Simmons, R., Thelwall, S., Stowe, J., Tessier, E., Groves, N., Dabrera, G., Myers, R., Campbell, C. N. J., Amirthalingam, G., Edmunds, M., Zambon, M., Brown, K. E., Hopkins, S., Chand, M. & Ramsay, M., 12 Aug 2021, In: New England Journal of Medicine. 385, 7, p. 585-594 10 p.

Research output: Contribution to journal › Article › peer-review

1989 Citations (Scopus)

Effects of threat and efficacy messages on expected adherence to decontamination protocols in an immersive simulated chemical incident: A randomized controlled experiment

Symons, C., Amlot, R., Carter, H. & Rubin, G. J., Mar 2021, In: Journal of Contingencies and Crisis Management. 29, 1, p. 54-76 23 p.

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Open Access

6 Citations (Scopus)

Epidemiological and clinical characteristics of early COVID-19 cases, United Kingdom of Great Britain and Northern Ireland

Boddington, N., Charlett, A., Elgohari, S., Byers, C., Coughlan, L., Vilaplana, T. G., Whillock, R., Sinnathamby, M., Panagiotopoulos, N., Letley, L., Macdonald, P., Vivancos, R., Edeghere, O., Shingleton, J., Bennett, E., Cottrell, S., McMenamin, J., Zambon, M., Ramsay, M. & Dabrera, G. & 2 others, Saliba, V. & Bernal, J. L., Mar 2021, In: Bulletin of the World Health Organization. 99, 3, p. 178-189 12 p.

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18 Citations (Scopus)

Epidemiology of confirmed covid-19 deaths in adults, england, march-december 2020

Brown, A., Heinsbroek, E., Kall, M., Allen, H., Beebeejaun, K., Blomquist, P., Campos-Matos, I., Campbell, C., Mohammed, H., Sinka, K., Lamagni, T., Phin, N., Dabrera, G., Charles, H., Foulkes, S., Mandal, S., Marchant, E., Nsonwu, O., O'Connell, A. M. & Russell, R. & 4 others, Simmons, R., Stowe, J., Thelwall, S. & Twohig, K., May 2021, In: Emerging Infectious Diseases. 27, 5, p. 1468-1471 4 p.

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21 Citations (Scopus)

59 Downloads (Pure)

Epidemiology of COVID-19 in prisons, England, 2020

Rice, W. M., Chudasama, D. Y., Lewis, J., Senyah, F., Florence, I., Thelwall, S., Glaser, L., Czachorowski, M., Plugge, E., Kirkbride, H., Dabrera, G. & Lamagni, T., Aug 2021, In: Emerging Infectious Diseases. 27, 8, p. 2183-2186 4 p.

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10 Citations (Scopus)

ESBL-producing strains isolated from imported cases of enteric fever in England and Wales reveal multiple chromosomal integrations of bla_CTX-M-15in XDR Salmonella Typhi

Nair, S., Chattaway, M. A., Langridge, G. C., Gentle, A., Day, M., Ainsworth, E. V., Mohamed, I., Smith, R., Jenkins, C., Dallman, T. & Godbole, G., 1 Jun 2021, In: Journal of Antimicrobial Chemotherapy. 76, 6, p. 1459-1466 8 p.

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24 Citations (Scopus)

Evidence for re-infection and persistent carriage of Shigella species in adult males reporting domestically acquired infection in England

Allen, H., Mitchell, H. D., Simms, I., Baker, K. S., Foster, K., Hughes, G., Dallman, T. & Jenkins, C., Jan 2021, In: Clinical Microbiology and Infection. 27, 1, p. 126.e7-126.e13 7 p.

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18 Citations (Scopus)

Experiences of supported isolation in returning travellers during the early COVID-19 response: A qualitative interview study

Carter, H., Weston, D., Greenberg, N., Oliver, I., Robin, C., Rubin, G. J., Wessely, S., Gauntlett, L. & Amlot, R., 23 Jul 2021, In: BMJ Open. 11, 7, 9 p., 050405.

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7 Citations (Scopus)

38 Downloads (Pure)

Healthcare-associated COVID-19 in England: A national data linkage study

Bhattacharya, A., Collin, S. M., Stimson, J., Thelwall, S., Nsonwu, O., Gerver, S., Robotham, J., Wilcox, M., Hopkins, S. & Hope, R., Nov 2021, In: Journal of Infection. 83, 5, p. 565-572 8 p.

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44 Citations (Scopus)

HIV prevalence and HIV clinical outcomes of transgender and gender-diverse people in England

Kirwan, P. D., Hibbert, M., Kall, M., Nambiar, K., Ross, M., Croxford, S., Nash, S., Webb, L., Wolton, A. & Delpech, V., Feb 2021, In: HIV Medicine. 22, 2, p. 131-139 9 p.

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