Mpox Clade IIb outbreak of 2022: an effective multi-sectoral public health response to an emerging infectious disease in England

Impact: Health impacts

Description of impact

In 2022/2023, UK Health security Agency (UKHSA) led a multisector response in
England to a global mpox outbreak that was subsequently declared a Public Health
Event of International Concern (PHEIC) by the World Health Organisation. The
outbreak was atypical due to the preponderance of cases among men who have sex
with men, evidence of sustained human-to-human transmission within/through highly
interconnected sexual networks and associated health equity concerns.
The response in England was complex and required extensive engagement with the
affected population(s). UKHSA scientists undertook rapid research to elucidate mpox
transmission patterns and to understand risk perception of gay, bisexual and men
who have sex with men (GBMSM) who were most affected. The scientists worked to
provide and iterate on the evidence to inform the design, delivery and monitoring of
the effectiveness of a targeted mpox vaccination programme, develop health
promotion messages to prevent further cases and improve uptake of vaccination
working with the National Health Service (NHS) and third-sector groups. They also
developed guidance for key populations, the general public, healthcare professionals
and service providers.
Category of impactHealth impacts